Moshe/Moszek was born in 1895, a son of Ella Jankiel and Rywka (Kalechsztajn) Nisenbaum.
His siblings were Ruchla, Abram, Kalman, Motel, Sura Gitla (Gutcha), Hena, and Aron. While most of his siblings left Poland, only he and Gutcha remained.
During the liquidation of the Ostrowiec Ghetto on October 11, 1942, Moshe decided not to join the forced gathering of the Jews at the Rynek (market square), and instead, went into hiding with this wife and children. Shortly thereafter, they were all caught, and Moshe was shot dead on the spot. Miraculously, his wife and children all survived the Holocaust and were liberated in 1945.